Twelve28 SkinRx
Healthy, radiant skin starts with personalized, prescription-strength solutions. SkinRx offers clinically backed treatments for acne, aging, hyperpigmentation and more.
SkinRx medications?
Twelve28Rx Creams for Targeted Skin Solutions
Clinically formulated prescription creams tailored to address acne, aging, hyperpigmentation, hormonal imbalances, and under-eye puffiness. Each blend combines medical-grade ingredients, such as tretinoin[Retin-A], niacinamide, clindamycin, estriol, and azelaic acid, for personalized, high-impact results. Trusted by providers, made for patients.
Treatment Plans
GLP-1 medications are a class of prescription drugs that not only improves blood sugar control but may also lead to weight loss. This class of drugs is commonly called glucagon-like peptide 1 (GLP-1) agonists. Weight loss can vary, depending on which GLP-1 drug you use and the dosage. Studies found people using Semaglutide and making lifestyle changes lost about 33.7 pounds (15.3 kilograms) versus 5.7 pounds (2.6 kilograms) in those who didn’t use the drug. GLP-1 medications are generally taken by an injection given weekly, depending on the drug.
Some of the more common side effects include:
Nausea, Vomiting, Diarrhea.
Side effects can often be mitigated by correctly titrating your dosage upward, so you’ll want to ensure that you are taking the medication exactly as prescribed by your provider to minimize risk and/or severity of side effects. Anti-nausea medications such as ondansetron (generic Zofran) are also helpful to assist in mitigating nausea.
Low blood sugar levels (hypoglycemia) are a more serious risk linked to the GLP-1 class of drugs. But the risk of low blood sugar levels often only goes up if you’re also taking another drug known to lower blood sugar at the same time, such as sulfonylureas or insulin. The GLP-1 class of drugs isn’t recommended if you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia. Lab studies have linked these drugs with thyroid tumors in rats. But until more long-term studies are done, the risk to humans isn’t known. The GLP-1 class of drugs is also not recommended if you’ve had pancreatitis.
References: https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/expert-answers/byetta/faq-20057955
Subscription Plan
A monthly supply, with automatic renewal every 1 month unless canceled.
Order Fulfillment
A licensed provider will review your order within 48 hours. Processing may take 7–10 business days, depending on our pharmacy partners. Once processed, your order ships via 2-day delivery.
These medications should be stored in the refrigerator between doses. GLP-1 medications are sensitive to temperature and could degrade if not stored properly.
You can take GLP-1 medications at any time during the day, without regard to meals. If your dosage is prescribed to take weekly, you should take your dose on the same day each week.
Please discuss your previous prescription and dosage with your provider during your medical intake process when enrolling and if medically appropriate, your provider will coordinate your dosage accordingly.
Disclaimer:
This product is prescribed by a licensed healthcare provider based on individual medical needs. It has not been evaluated or approved by the U.S. Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease. Compounded medications are not FDA-approved, and their safety and effectiveness have not been independently verified by the FDA. This information is provided for educational purposes only and is not a substitute for professional medical advice.
Dedicated doctors in every state
Twelve28Rx delivers convenient, clinically guided care solutions like weight loss, hair restoration, and overall wellness. Our licensed providers offer personalized treatment plans you can access from the comfort and privacy of your home, no waiting rooms, no guesswork, just expert care made simple.
Get Your Prescription
Contact us
Getting started with Twelve28Rx is easy. We offer customized online visits for each medical condition we treat, enabling our healthcare providers to focus exclusively on the patient’s symptoms and medical history.
Online Consultation
Once you’ve reached out to us, you can consult with one of our specialized healthcare professionals. If you qualify, our healthcare professionals will provide you with clinically proven treatments
Rush “No Contact” Delivery
We offer rush “no contact” delivery of your prescribed medications and treatment products. We prioritize your convenience and privacy, ensuring that your treatments are delivered promptly to your preferred address.
FAQ's
How should I apply these creams?
Apply a thin layer to clean, dry skin once daily at night, or as directed by your provider. Wash hands before and after use. Avoid the eye area unless specifically directed.
Can I use more than one formula at a time?
In most cases, only one prescription cream should be used at a time unless your provider advises otherwise. Combining actives without guidance can increase irritation.
Are these prescription-only products?
Yes. These formulas are compounded and require a prescription. Your provider will determine the most suitable option for your skin.
Are these safe for sensitive skin?
Many formulations include ingredients that can cause irritation, especially in sensitive skin. Your provider may recommend easing in with every-other-night use to build tolerance.
What should I expect during the first few weeks?
Mild redness, dryness, or purging (temporary acne flare) is common, especially with tretinoin or benzoyl peroxide. These effects usually subside as your skin adjusts.
Can I use these products with other skincare or makeup?
Yes, but avoid layering other active ingredients (like AHAs or BHAs) without professional guidance. Always apply sunscreen daily when using products with tretinoin or other acids.
Are these creams safe during pregnancy or breastfeeding?
Some ingredients (like tretinoin, spironolactone, hydroquinone, or estriol) are not recommended during pregnancy or nursing. Always consult your provider before use.